A Life-Saving Medication, Ready When It’s Needed Most
Opioid overdose can happen anywhere — in a workplace, a public restroom, a parking lot — and it can happen to someone using prescribed medication, not just illicit drugs. NARCAN Nasal Spray gives anyone nearby, trained or not, the ability to respond immediately. As an opioid antagonist, naloxone works by rapidly binding to opioid receptors in the brain, reversing the slowed or stopped breathing that makes opioid overdose fatal.
FDA-Approved for Use Without a Prescription
NARCAN Nasal Spray was the first naloxone product ever approved by the FDA for over-the-counter, nonprescription use — a milestone specifically intended to make this life-saving medication as accessible as possible in the places overdoses actually happen. No prescription, medical training, or special certification is required to purchase, stock, or administer it.
Simple Enough for Anyone to Use
Each package contains 2 single-dose nasal spray devices, each delivering a single 4mg dose. The three-step process is designed to be usable under stress by someone with no medical background:
- CHECK — Look for signs of overdose: the person won’t wake up, is very sleepy, or isn’t breathing well. Yell “Wake up!” and shake the person gently.
- GIVE — Hold the device with your thumb on the plunger, insert the nozzle into either nostril, and press firmly to deliver the dose.
- CALL — Call 911 immediately, even if the person responds to the first dose.
NARCAN is safe to use even if opioids turn out not to be present, meaning a responder never needs to be certain before acting.
What Happens After Administration
When naloxone reverses an overdose, the person may experience withdrawal-like symptoms upon waking — shaking, sweating, nausea, or agitation. This is an expected part of the medication working, not a sign of a problem.
Important Safety Information
Active ingredient (per spray): Naloxone Hydrochloride 4mg
Purpose: Emergency treatment of opioid overdose
Important reminder: NARCAN Nasal Spray is not a substitute for emergency medical care. Always call 911 after administering, even if the person seems to recover.
Store at room temperature or refrigerated, between 36°F and 77°F (2°C to 25°C). Do not freeze. Avoid excessive heat above 104°F. Keep out of reach of children when not in use for an emergency.
Features at a Glance
- FDA-approved, no prescription required
- 2 single-dose nasal spray devices per box, 4mg each
- No assembly, priming, or training required
- Safe to administer even if opioid use isn’t confirmed
- Can be given by coworkers, bystanders, or family members
- Compact size for first aid cabinets, kits, or desk storage
Built For
Workplace opioid emergency response programs • Offices, warehouses, and job sites • Schools and public facilities • Overdose prevention kits and wall-mounted cabinets • Anyone building a complete emergency response station
Specifications
| Manufacturer | Emergent BioSolutions (NARCAN®) | Active Ingredient | Naloxone Hydrochloride, 4mg per spray | NDC | 69547-627-02 | Devices Per Package | 2 single-dose nasal spray devices | Route of Administration | Nasal | Prescription Required | No (FDA-approved OTC) | Storage | 36°F–77°F (2°C–25°C); do not freeze | Drug Category | OTC (over-the-counter) |
